منابع مشابه
Topical Corticosteroids: Pharmacology
Topical corticosteroids are widely used for inflammatory and hyperproliferative disorders in dermatology. Numerous topical corticosteroids with high local activity have been developed over the years, with a focus to develop drugs with high efficacy locally and minimum risk for adverse drug reactions. They are available in a number of formulations. Their therapeutic effects are a result of their...
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Purpose Corticosteroids remain the mainstay of treatment for inflammatory diseases almost 80 years after their first clinical use. Topical ophthalmic formulations of corticosteroids have been available to treat disease of the anterior segment of the eye, but the approval of corticosteroids to treat vitreoretinal diseases, including vein occlusion, diabetic macular edema, and uveitis, has occurr...
متن کاملIs the pharmacology of corticosteroids in the lung modified by age?
WHAT WE NEED TO KNOW: Is the lung in older patients with asthma less responsive to inhaled and systemic corticosteroids? (While anecdotal observations suggest this may be the case, no well conducted studies document the phenomenon.) WHAT WE NEED TO DO: Carefully plan a clinical study to compare corticosteroid responsiveness between older people with asthma and their younger counterparts. Select...
متن کاملCorticosteroids in Infectious Diseases
Accumulated data based on experiences with curtico,teroids in the management uf infectious diseases, have proved that they are very dfective and ,afe drugs provided that are administered properly. The Corticosteroids arc administered mainly bec,1usc o; antitoxic, antiimflammatory a11d antiallcrgic effects, the cndotoxius are ncuturalized, generalized body reactions are diminished, damaged t...
متن کاملPharmacology and Toxicology of Leflunomide
Leflunomide (LEF), used for rheumatoid arthritis, inhibits dihydro-orotate dehydrogenase (DHODH) and tyrosine kinase (TK) enzymes and has anti-inflammatory, lymphocyte proliferation regulatory, immunosuppression and chondroprotective effects. The most common adverse effects are gastrointestinal disorders, weight loss, hypertension, skin infection, and neurological and hematological toxicity. It...
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ژورنال
عنوان ژورنال: Respiratory Medicine
سال: 1998
ISSN: 0954-6111
DOI: 10.1016/s0954-6111(98)90280-3